Bio-Microfluidics

Research Works

Welcome to the "Research Works" section of our research lab's website. Here, we showcase the exciting projects and research initiatives that drive our passion for discovery and innovation. Our dedicated team of researchers, led by Dr. Abhishek Raj, is committed to pushing the boundaries of knowledge and making meaningful contributions to our respective fields of Bio-Microfluidics. In our pursuit of knowledge, innovation, and excellence, the Publication Section of our website serves as a window into the depth and breadth of our research endeavors. Here, we proudly showcase our contributions to the scientific community, our commitment to advancing knowledge, and our dedication to making a meaningful impact in our fields of expertise.

Publications

The research conducted at our Bio-microfluidics laboratory has led to significant contributions in the fields of microfluidics, biology, and biotechnology. Our dedicated team of researchers, students, and collaborators have published their findings in renowned scientific journals, conferences, and books.

Works
Journal Articles
Conferences
Book Chapters
Patents

Journal Articles


Sl. No. Articles
24 Amit, K., Assam, A., & Raj, A. Droplet Migration through Deformable Stenosed Microchannel: Dynamics and Blockage. 35(10). (Editor's Pick)
Physics of Fluids (Impact factor: 4.98)
23 Haider, S.A., Kumar, G., Goyal, T & Raj, A. Stiffness estimation and classification of biological cells using constriction microchannel: poroelastic model and machine learning. 28, 14 (2024).
Microfluidics and Nanofluidics (Impact factor: 3.09)
22 Agarwal, D., Kamble, Y., Raj, A. et al. Biomechanical parameter estimation using untethered nonprehensile magnetic microrobot. (2023)
J Micro-Bio Robot (Impact factor: 2.3)
21 Rohit, Haider, S.A. & Raj, A. ANN-aided stiffness characterization of thin membranes using droplet motion. (2023).
Acta Mech(Impact factor: 2.7)
20 Pabi, S., Khan, M., Jain, S. K., Sen, A. K., & Raj, A. Effect of stenotic shapes and arterial wall elasticity on the hemodynamics. 35(10).
Physics of Fluids (Impact factor: 4.98)
19 Raj, A., Ramirez, K., Young, K. M., Stone, N., Shankles, P., Nadeem Rajab Ali, M., Compton, A. M., Lam, W., Alexeev, A., & Sulchek, T. (2023). Label-free microfluidic isolation of functional and viable lymphocytes from peripheral blood mononuclear cells. 7(5), 054102.
Biomicrofluidics (Impact factor: 3.27)
18 Amit, K., Assam, A., & Raj, A. (2023). Pressure-flow characteristics of a microchannel combining super-hydrophobicity and wall compliance. 27, 64.
Microfluidics and Nanofluidics (Impact factor: 2.8)
17 Haider, S. A., & Raj, A. (2023). Liquid drops on compliant and non-compliant substrates: an ellipsoid-based fitting for approximating drop shape and volume. 27(7), 49.
Microfluidics and Nanofluidics (Impact factor: 3.09)
16 Haider, S. A., & Raj, A. (2023). Retention analysis of droplets over compliant substrates. 673, 131800.
Colloids and Surfaces (Impact factor: 5.2)
15 Kamble, Y., Raj, A., & Thakur, A. (2023). Artificial Neural Network-Aided Computational Approach for Mechanophenotyping of Biological Cells Using Atomic Force Microscopy. 145(7), 071007.
Journal of Biomechanical Engineering (Impact factor: 1.7)
14 Chrit, F. E., Raj, A., Young, K. M., Stone, N. E., Shankles, P. G., Lokireddy, K., ... & Sulchek, T. (2021). Microfluidic platform to transduce cell viability to distinct flow pathways for high-accuracy sensing. 6(10), 3789-3799.
ACS Sensors (Impact factor: 9.618)
13 Stone, N.E., Raj, A., Young, K.M. et al. (2021). Label-free microfluidic enrichment of cancer cells from non-cancer cells in ascites. 11, 18032.
Scientific Reports (Impact factor: 4.6)
12 Lathika, S., Raj, A., & Sen, A. K. (2021). LSPR based on-chip detection of dengue NS1 antigen in whole blood. 11(53), 33770-33780.
RSC Advances (Impact factor: 4.036)
11 Islam, M., Raj, A., McFarland, B., Brink, H. M., Ciciliano, J., Fay, M., ... & Sulchek, T. (2020). Stiffness based enrichment of leukemia cells using microfluidics. 4(3).
APL Bioengineering (Impact factor: 6.586)
10 Liu, A., Yu, T., Young, K., Stone, N., Hanasoge, S., Kirby, T. J., ... & Sulchek, T. (2020). Cell mechanical and physiological behavior in the regime of rapid mechanical compressions that lead to cell volume change. 16(2), 1903857.
Nano-Micro Small (Impact factor: 13.3)
09 Hazra, S., Jayaprakash, K. S., Pandian, K., Raj, A., Mitra, S. K., & Sen, A. K. (2019). Non-inertial lift induced migration for label-free sorting of cells in a co-flowing aqueous two-phase system. 2574-2583.
Analyst (Impact factor: 5.227)
08 Raj, A., Suthanthiraraj, P. P., & Sen, A. K. (2018). Pressure-driven flow through PDMS-based flexible microchannels and their applications in microfluidics. 22, 1-25.
Microfluidics and Nanofluidics (Impact factor: 2.8)
07 Banerjee, U., Raj, A., & Sen, A. K. (2018). Dynamics of aqueous ferrofluid droplets at coflowing liquid-liquid interface under a non-uniform magnetic field. 113(14).
Applied Physics Letters (Impact factor: 3.971)
06 Raj, A., & Sen, A. K. (2018). Entry and passage behavior of biological cells in a constricted compliant microchannel. 8(37), 20884-20893.
RSC Advances (Impact factor: 4.036)
05 Raj, A., Dixit, M., Doble, M., & Sen, A. K. (2017). A combined experimental and theoretical approach towards mechanophenotyping of biological cells using a constricted microchannel. 17(21), 3704-3716.
Lab on a Chip (Impact factor: 7.517)
04 Raj, A., & Sen, A. K. (2016). Flow-induced deformation of compliant microchannels and its effect on pressure–flow characteristics. 20(2), 31.
Microfluidics and Nanofluidics (Impact factor: 2.8)
03 Sajeesh, P., Raj, A., Doble, M., & Sen, A. K. (2016). Characterization and sorting of cells based on stiffness contrast in a microfluidic channel. 6(78), 74704-74714.
RSC Advances (Impact factor: 4.036)
02 Raj, A., Halder, R., Sajeesh, P., & Sen, A. K. (2016). Droplet generation in a microchannel with a controllable deformable wall. 20, 1-16.
Microfluidics and Nanofluidics (Impact factor: 2.8)
01 Iyer, V., Raj, A., Annabattula, R. K., & Sen, A. K. (2015). Experimental and numerical studies of a microfluidic device with compliant chambers for flow stabilization. 25(7), 075003.
Micromechanics and Microengineering (Impact factor: 2.40)

Presented Conferences


Sl. No. Conferences
21 Kumar Amit, Ashwani Assam, and Abhishek Raj. Analysis of a Deformable Stenosed Microchannel for Cell Migration: A Guide for Blockage Prediction.
Proceedings of the 27th National and 5th International ISHMT-ASTFE Heat and Mass Transfer Conference, (IHMTC), Paper ID: IHMTC2023-332, December 14-17, 2023, IIT Patna, Patna-801106, Bihar, India.
20 Kumar Amit, Ashwani Assam, and Abhishek Raj. Heat Transfer Analysis in Pulsating Laminar Flow for Biological Applications.
Proceedings of the 27th National and 5th International ISHMT-ASTFE Heat and Mass Transfer Conference, Conference, (IHMTC), Paper ID: IHMTC2023-287, December 14-17, 2023, IIT Patna, Patna-801106, Bihar, India.
19 Ashish Sonker, Rohit, and Abhishek Raj. Investigation Of Dynamics Of Non Newtonian Droplet Over Thin Compliant PDMS Membrane.
Proceedings of the 27th National and 5th International ISHMT-ASTFE Heat and Mass Transfer Conference, (IHMTC), Paper ID:IHMTC2023-297 December 14-17, 2023, IIT Patna, Patna-801106, Bihar, India.
18 Syed Ahsan Haider, Aathira Sarath Chandran, Rohit, and Abhishek Raj. Facile Fabrication of PDMS Microparticles Using Fluid Shearing Based Methods.
Proceedings of the 27th National and 5th International ISHMT-ASTFE Heat and Mass Transfer Conference, (IHMTC), Paper ID: IHMTC2023-320 December 14-17, 2023, IIT Patna, Patna-801106, Bihar, India.
17 Syed Ahsan Haider, Abhishek Raj. Ellipsoid Based Model for Volume Measurement of Droplets Placed Over Rigid and Compliant Substrates.
Proceedings of the 27th National and 5th International ISHMT-ASTFE Heat and Mass Transfer Conference, (IHMTC), Paper ID: IHMTC2023-318 December 14-17, 2023, IIT Patna, Patna-801106, Bihar, India.
16 Souvik Pabi, Md. Kaleem Khan, and Abhishek Raj. Effect of Womersley number on the hemodynamics of a stenotic carotid artery with heat generation.
Proceedings of the 27th National and 5th International ISHMT-ASTFE Heat and Mass Transfer Conference, (IHMTC), Paper ID: IHMTC2023-282 December 14-17, 2023, IIT Patna, Patna-801106, Bihar, India.
15 Kumar Amit, Ashwani Assam and Abhishek Raj. Search for a Durable Superhydrophobic Microchannel for Intesive Drag Reduction.
Proceedings of the 1st Indian Conference on Micro Nano Fluidics (ICOM) 2023, Paper ID: ICOM0075, Sep 29 – Oct 1, 2023, IIT Madras, Chennai-600036, Tamil Nadu, India
14 Rohit, Syed Ahsan Haider and Abhishek Raj. Droplet Motion Over Thin Compliant PDMS Membrane.
Proceedings of the 1st Indian Conference on Micro Nano Fluidics (ICOM) 2023, Paper ID: ICOM0054, Sep 29 – Oct 1, 2023, IIT Madras, Chennai-600036, Tamil Nadu, India
13 Syed Ahsan Haider and Abhishek Raj. Volume estimation of droplets placed over compliant and non-compliant substrate.
Proceedings of the 1st Indian Conference on Micro Nano Fluidics (ICOM) 2023, Paper ID: ICOM0096, Sep 29 – Oct 1, 2023, IIT Madras, Chennai-600036, Tamil Nadu, India
12 Syed Ahsan Haider and Abhishek Raj. Mechanophenotyping Of Biological Cells Considering Poroelasticity.
Proceedings of the 1st Indian Conference on Micro Nano Fluidics (ICOM) 2023, Paper ID: ICOM0098, Sep 29 – Oct 1, 2023, IIT Madras, Chennai-600036, Tamil Nadu, India
11 Syed Ahsan Haider, Rohit, and Abhishek Raj. Effect of substrate compliance on the droplet retention.
Proceedings of the 1st Indian Conference on Micro Nano Fluidics (ICOM) 2023, Paper ID: ICOM0097, Sep 29 – Oct 1, 2023, IIT Madras, Chennai-600036, Tamil Nadu, India
10 Rohit, Syed Ahsan Haider, and Abhishek Raj. Droplet Motion Over Compliant Membrane Predicts the Stiffness of Membrane.
11th International Conference on Multiphase Flow, ICMF 2023, Paper No: 419, Kobe, Japan, April 2–7, 2023
9 Syed Ahsan Haider, Rohit, and Abhishek Raj. Retention Dynamics of Droplets over Soft Compliant Substrates.
11th International Conference on Multiphase Flow, ICMF 2023, Paper No: 421, Kobe, Japan, April 2–7, 2023
8 Kumar Amit, Ashwani Assam, and Abhishek Raj. Dynamics of droplet motion in stenosed deformable microchannel.
11th International Conference on Multiphase Flow, ICMF 2023, Paper No: 423, Kobe, Japan, April 2–7, 2023
7 Syed Ahsan Haider, Rohit, and Abhishek Raj. Retention Force of Substrates.
Proceedings of the 9th International and 49th National Conference on Fluid Mechanics and Fluid Power, (FMFP), Paper No: 323, December 14-16, 2022, IIT Roorkee, Roorkee-247667, Uttarakhand, India
6 Kartikay Gupta, Neeraj Goyal, Syed Ahsan Haider, Rohit, and Abhishek Raj. Machine Learning aided Determination of Young’s Modulus of Polydimethylsiloxane (PDMS) Membranes using Droplet Indentation.
Proceedings of the 9th International and 49th National Conference on Fluid Mechanics and Fluid Power, (FMFP), Paper No: 1421 December 14-16, 2022, IIT Roorkee, Roorkee-247667, Uttarakhand, India
5 Rohit, Syed Ahsan Haider, and Abhishek Raj. ANN Aided Prediction of Young’s Modulus of PDMS Membrane Using Droplet Motion.
Proceedings of the 9th International and 49th National Conference on Fluid Mechanics and Fluid Power, (FMFP), Paper No: 7202, December 14-16, 2022, IIT Roorkee, Roorkee-247667, Uttarakhand, India
4 Kumar Amit, Ashwani Assam, and Abhishek Raj. Pressure flow characteristics of a deformable microchannel with a superhydrophobic wall.
Proceedings of the 9th International and 49th National Conference on Fluid Mechanics and Fluid Power, (FMFP), Paper No:2897, December 14-16, 2022, IIT Roorkee, Roorkee-247667, Uttarakhand, India
3 Kumar Amit, Ashwani Assam, and Abhishek Raj. Role of deformability and super-hydrophobicity in the microchannel.
26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022, Chemical and Biological Microsystems Society, 23-27 October, Hangzhou, China
2 Kumar Amit, Ashwani Assam, and Abhishek Raj. Hydrodynamics resistance of stenosed deformable microchannel for droplet migration.
Proceedings of the 9th International and 49th National Conference on Fluid Mechanics and Fluid Power, (FMFP), Paper No: 2589 December 14-16, 2022, IIT Roorkee, Roorkee-247667, Uttarakhand, India
1 Souvik Pabi, Md. Kaleem Khan, and Abhishek Raj. Numerical investigation of the pulsatile flow of non-Newtonian biofluid through a rigid stenosed channel.
Proceedings of the 9th International and 49th National Conference on Fluid Mechanics and Fluid Power, (FMFP), Paper No: 2589 December 14-16, 2022, IIT Roorkee, Roorkee-247667, Uttarakhand, India.

Book Chapters


Sl. No. Details
1 Rohit, Raj, A. (2023). Thermoporation Based Drug Delivery Systems. In: Santra, T.S., Shinde, A.U.S. (eds) Advanced Drug Delivery. Studies in Mechanobiology, Tissue Engineering and Biomaterials, vol 26. Springer, Singapore.
2 Pabi, S., Khan, M.K., Alexeev, A., Sulchek, T., Raj, A. (2023). Electroporation-Based Drug Delivery. In: Santra, T.S., Shinde, A.U.S. (eds) Advanced Drug Delivery. Studies in Mechanobiology, Tissue Engineering and Biomaterials, vol 26. Springer, Singapore.
3 Haider, S.A., Alexeev, A., Sulchek, T., Raj, A. (2023). Mechanoporation-Based Drug Delivery. In: Santra, T.S., Shinde, A.U.S. (eds) Advanced Drug Delivery. Studies in Mechanobiology, Tissue Engineering and Biomaterials, vol 26. Springer, Singapore.

Patents


Sl. No. Details
1 A.K. Sen, A. Srivastava, R. Gaikward, Karthick S, Jayaprakash KS, A. Raj, S. Maria, P. Shivhare, micro-facs for detection and isolation of target cells, Application filed with the World Intellectual Property Organization International Bureau, Publication Number WO2018185781A1, Application number PCT/IN2018/050194, International Publication Date 11/10/2018. https://patents.google.com/patent/WO2018185781A1/en